This chapter examines the ways in which race can been understood as a fundamental ordering principle of world politics. It explores how the histories of European imperialism and colonialism are crucial for understanding the global impact of race, and whether contemporary world politics is less racist than it was in the past. It also considers the relationship between race, biology, and culture. The chapter concludes by discussing the historical processes that gave rise to race, some key debates around the conceptualization of race, and how race continues to order world politics. Two case studies are presented: the first is about the Universal Negro Improvement Association and African Communities League (UNIA-ACL) and the second is about caste and Dalits in India. There is also an Opposing Opinions box that asks whether racism emerged as a consequence of the slave trade.