This chapter focuses on the Middle East during the post-Cold-War era. It introduces some the key themes that have come to dominate contemporary international relations of the Middle East: oil; new and old conflicts; the impacts of globalization; and religio-politics. In considering the major security patterns and trends in the Middle East, one finds a number of enduring issues, such as the Arab–Israeli conflict and border disputes. At the same time, one can see elements of change, both within these conflicts and with the emergence of recent threats, such as Iranian nuclearization, with profound consequences for regional alliance structures. As old and new security issues mingle in the geopolitical order, events of the past few years reflect a region dominated by conflict clusters. It is no surprise then that the Middle East remains a highly militarized region.