This chapter examines the importance of comparative politics for understanding human rights practices. Comparative politics has advanced our knowledge of why states sometimes violate internationally recognized human rights. Both domestic incentives and exclusionary ideologies increase the likelihood of rights violations. On the other hand, comparative politics has attempted to explain human rights protection, showing how domestic structures (both societal groups and state institutions) can influence reform efforts. This chapter first consider alternative logics of comparison, including the merits of comparing a small versus a large number of cases and human rights within or across regions. It then explores the leading domestic-level explanations for why human rights violations occur. It also describes the use of domestic–international linkages to explain otherwise perplexing human rights outcomes. Finally, it analyses the ways in which, in the context of globalization, comparative politics shapes human rights practices.