This chapter deals with the first step of the research process: the formulation of a well-crafted research question. It explains why political research should begin with a research question and how a research question structures the research process. It discusses the difference between a topic or general question, on the one hand, and a focused research question, on the other. It also considers the question of where to find and how to formulate research questions, the various types of questions scholars ask, and the role of the ‘literature review’ as a source and rationale for research questions. Finally, it describes a tool called the ‘research vase’ that provides a visualization of the research process, along with different types of questions: descriptive, explanatory, predictive, prescriptive, and normative.