This chapter examines the historical evolution of U.S. foreign policy in Africa. It first considers the history of U.S.–Africa relations, particularly during the Cold War era of U.S.–Soviet Union superpower rivalry. It then turns to the immediate post-Cold War era, in which a New World Order — a vision in which the United States and the United Nations could combine to establish freedom and respect for all nations — held out the possibility of positive U.S. involvement in Africa. It also discusses American policy towards Africa after 9/11, focusing on President George W. Bush’s efforts to incorporate Africa into Washington’s global strategic network as part of the new war on terror. The chapter concludes with an assessment of Barack Obama’s peace diplomacy as an approach to the civil war in Sudan.